Mouse TEX19.1 Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # FAB6645AFP488

R&D Systems

Key Product Details

Species Reactivity

Mouse

Applications

Immunocytochemistry

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # 678803
View all TEX19.1 Primary Antibodies »

Product Specifications

Specificity

Detects mouse TEX19.1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human TEX19, recombinant mouse (rm) TEX19.2, or rmTEX11 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse TEX19.1 Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TEX19.1

Testis-expressed protein 19.1 (TEX19.1; also Tex19a and Tex19) is a 40 kDa pluripotent stem cell molecule. Mouse TEX19.1 is 351 amino acids (aa) in length.  The first conserved domain is localized on the N-terminal boundary of the protein and is 58 residues long.  It is known as the MCP domain, and begins with an invariant MCPPVS motif. The second conserved domain, known as the VPTEL domain, begins with an invariant VPTEL motif and is 38 amino acids long. Mouse TEX19.1 shares 70% and 24% aa identity with rat and human Tex19.1, respectively. The protein is restricted to mammals and is expressed in testis, placenta, and ovary.  It is expressed in early embryo and is later limited to the germ line. Tex19.1 has been shown to present in the cytoplasm of spermatogonia and early spermatocytes in adult mouse testes (1). The precise function of TEX19.1 is still unknown, but it is thought to be a new transcription factor regulating target genes responsible for pluripotency or it has a role in controlling the chromatin architecture of the pluripotent nucleus.

References

  1. Ollinger R. et. al. (2008) PLos 4(9):e1000199.

Long Name

Testis Expressed 19.1

Alternate Names

Tex19a

Entrez Gene IDs

73679 (Mouse)

Gene Symbol

TEX19.1

UniProt

Q99MV2

Additional TEX19.1 Products

Product Documents for Mouse TEX19.1 Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Mouse TEX19.1 Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Primordial and Mature Germ Cells

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