Mouse VEGFR1/Flt-1 (NP_034358) VersaClone cDNA

Name: Mouse VEGFR1/Flt-1 (NP_034358) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1267
Price: 1079 USD
Availability: InStock

R&D Systems | Catalog # RDC1267

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Mouse

Accession Number

NP_034358

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: VEGFR1/Flt-1

VEGFR1 (vascular endothelial growth factor receptor 1; Flt-1) binds to VEGF-A, VEGF-B, and PlGF and functions in vasculogenesis, angiogenesis, lymphangiogenesis, and wound healing. It is expressed on endothelial cells, osteoblasts, placental trophoblasts, renal mesangial cells, and some hematopoietic stem cells. It can heterodimerize with VEGFR2 and modulate VEGFR2 mediated endothelial cell proliferation and vessel branching. VEGFR1 engagement on monocyte/macrophage lineage cells enhances their migration, and release of growth factors and cytokines.