Catalog Number: 2502
Alternate Names: 5-Iodo-UDP trisodium salt
Chemical Name: 5-Iodouridine-5'-O-diphosphate trisodium salt
Biological Activity
Selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble in water (supplied pre-dissolved at a concentration of 10mM)
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor.
    Besada et al.
    J.Med.Chem., 2006;49:5532
  2. Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation.
    Mamedova et al.
    Pharmacol.Res., 2008;58:232
  3. Development of selective agonists and antagonists of P2Y receptors.
    Jacobson et al.
    Purinerg.Sig., 2009;5:75
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