MRS 2693 trisodium salt
Tocris Bioscience | Catalog # 2502
Selective P2Y6 agonist
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Key Product Details
Description
Selective P2Y6 agonist
Alternative Names
5-Iodo-UDP trisodium salt
Product Description
MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.
Product Specifications for MRS 2693 trisodium salt
Molecular Weight
596.00
Formula
C9H10IN2Na3O12P2
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
5-Iodouridine-5'-O-diphosphate trisodium salt
CAS Number
1448858-83-0
PubChem ID
90488768
InChI Key
QWGVSYFNEAILDQ-FCIXCQMASA-K
SMILES
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N1C=C(I)C(=O)NC1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.
- Mamedova Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol.Res. 2008 PMID: 18805489
- Jacobson Development of selective agonists and antagonists of P2Y receptors. Purinerg.Sig.
- Besada Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. J.Med.Chem. 2006 PMID: 16942026
Product Documents for MRS 2693 trisodium salt
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for MRS 2693 trisodium salt
For research use only
Related Research Areas
Citations for MRS 2693 trisodium salt
Customer Reviews for MRS 2693 trisodium salt (1)
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Species: HumanAssay Type: In VitroCell Line/Tissue: 1321N1Verified Customer | Posted 09/09/2021Used MRS 2693 in a fluorescence-based intracellular calcium assay, and the agonist came pre-dissolved in water to a concentration of 10 mM.
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