MRT 68921 dihydrochloride

Key Product Details

Product Description

MRT 68921 dihydrochloride is a potent ULK inhibitor (IC₅₀ values are 1.1 and 2.9 nM for ULK2 and ULK1, respectively). Inhibits autophagy in mouse embryonic fibroblasts.

Product Specifications for MRT 68921 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for MRT 68921 dihydrochloride

The following data is based on the product molecular weight 507.50.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.97 mL	9.85 mL	19.70 mL
5 mM	0.39 mL	1.97 mL	3.94 mL
10 mM	0.20 mL	0.99 mL	1.97 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Petherick Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J.Biol.Chem. 2015 PMID: 25833948

Product Documents for MRT 68921 dihydrochloride