MYCBP2 Antibody

Novus Biologicals | Catalog # NB100-97841

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Western Blot, Immunoprecipitation (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all MYCBP2 Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 2425 and 2475 of human protein associated with Myc using the numbering given in entry NP_055872.3 (GeneID 23077).

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

510 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MYCBP2 Antibody

Western Blot: MYCBP2 Antibody [NB100-97841]

Western Blot: MYCBP2 Antibody [NB100-97841]

Western Blot: MYCBP2 Antibody [NB100-97841] - Whole cell lysate (5, 15, 50 ug loaded) from HeLa cells probed with anti-MYCBP2 antibody at 0.04 ug/ml.

Applications for MYCBP2 Antibody

Application
Recommended Usage

Western Blot

1:2000-1:10000
Application Notes
IP Not recommended, use rabbit anti-PAM antibody NB100-97840.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: MYCBP2

In addition to its possible functions as a facilitator of Myc activated transcription, PAM (protein associated with Myc) has also been shown to play a role in mTOR signaling. PAM functions as an E3 ubiquitin ligase for tuberin (TSC2), a negative regulator of the mTOR pathway. Additionally PAM has been shown to function as a guanosine exchange factor (GEF) for Rheb and to facilitate sphingosine-1-phosphate signaling in the mTOR pathway. Alternative names for PAM include Myc-binding protein 2, MYCBP2, Pam/highwire/rpm-1 protein, and KIAA0916.

Alternate Names

DKFZp686M08244, EC 6.3.2.-, FLJ10106, FLJ21646, KIAA0916FLJ13826, MYC binding protein 2, Myc-binding protein 2, Pam/highwire/rpm-1 protein, PAMFLJ21597, probable E3 ubiquitin-protein ligase MYCBP2, Protein associated with Myc

Entrez Gene IDs

23077 (Human)

Gene Symbol

MYCBP2

UniProt

O75592 (Human)

Additional MYCBP2 Products

Product Documents for MYCBP2 Antibody

Certificate of Analysis

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Product Specific Notices for MYCBP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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