Mycophenolate mofetil

Catalog # Availability Size / Price Qty
Mycophenolate mofetil | CAS No. 128794-94-5 | Dehydrogenase Inhibitors
1 Image
Description: Inosine monophosphate dehydrogenase (IMPDH) inhibitor

Chemical Name: 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester

Purity: ≥99%

Product Details
Citations (1)

Biological Activity

Mycophenolate mofetil is an immunosuppressant prodrug of mycophenolic acid (MPA) (Cat. No. 1505). Hydrolyzed by esterases to release MPA, a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). Used to prevent organ rejection after transplantation. Displays inhibitory activity of lymphocyte functions. Inhibits type 1 collagen expression, enhances MMP-1 expression, and reduces α-smooth muscle actin gene expression.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in ethanol
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Purine metabolism and immunosuppressive effects of mycophen. mofetil (MMF).
    Allison and Eugui
    Clin.Transplant., 1996;10:77
  2. In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophen. mofetil.
    Roos et al.
    J.Pharm.Exp.Ther., 2007;321:583

Product Datasheets

Or select another batch:
View Batch
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Mycophenolate mofetil

The citations listed below are publications that use Tocris products. Selected citations for Mycophenolate mofetil include:

1 Citation: Showing 1 - 1


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Mycophenolate mofetil

There are currently no reviews for this product. Be the first to review Mycophenolate mofetil and earn rewards!

Have you used Mycophenolate mofetil?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.