Mycophenolic acid

Tocris Bioscience | Catalog # 1505

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
Tocris Bioscience

Key Product Details

Description

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor
View all Dehydrogenase Inhibitors »

Product Description

Mycophenolic acid is an immunosuppressive agent with antiviral and antitumor effects in vitro and in vivo. Potently inhibits inosine monophosphate dehydrogenase (IMPDH), thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. Reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Product Specifications for Mycophenolic acid

Molecular Weight

320.34

Formula

C17H20O6

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid

CAS Number

24280-93-1

PubChem ID

446541

InChI Key

HPNSFSBZBAHARI-RUDMXATFSA-N

SMILES

COC1=C(C)C2=C(C(=O)OC2)C(O)=C1C\C=C(/C)CCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.03 100

Preparing Stock Solutions for Mycophenolic acid

The following data is based on the product molecular weight 320.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.12 mL 15.61 mL 31.22 mL
5 mM 0.62 mL 3.12 mL 6.24 mL
10 mM 0.31 mL 1.56 mL 3.12 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Product Documents for Mycophenolic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Mycophenolic acid

For research use only

Related Research Areas

Redox Enzymes

Citations for Mycophenolic acid

Customer Reviews for Mycophenolic acid (1)

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  • Used as an IMPDH inhibitor
    Name: Timothy Ryan
    Species: Rat
    Assay Type: Ex Vivo
    Cell Line/Tissue: Primary hippocampal neurons
    Verified Customer | Posted 09/30/2024
    The drug was incubated at 2 μM for 2 h to deplete intracellular GTP.

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