The alpha and beta forms of Neurexins 1 - 3 are transmembrane neuronal glycoproteins which are transcribed from each of the three NRXN genes from alternate promoters. The interaction of presynaptic Neurexins with postsynaptic Neuroligins is important for synaptic development and is restricted to particular combinations of splice forms of each binding partner.
Neurexin 1 beta/NXRN1b Antibody [DyLight 550]
Novus Biologicals | Catalog # AF4524L
Key Product Details
Species Reactivity
Rat
Applications
Western Blot
Label
DyLight 550 (Excitation = 562 nm, Emission = 576 nm)
Antibody Source
Polyclonal Sheep IgG
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Neurexin 1 beta /NXRN1b
Ala47-Thr392
Accession # Q63373
Ala47-Thr392
Accession # Q63373
Specificity
Detects rat Neurexin 1 beta /NXRN1b in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross‑reactivity with recombinant rat Neurexin 1 alpha is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Neurexin 1 beta/NXRN1b Antibody [DyLight 550]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Neurexin 1 beta/NXRN1b
Alternate Names
NXR1B, NXRN1b
Gene Symbol
NRXN1
Additional Neurexin 1 beta/NXRN1b Products
Product Documents for Neurexin 1 beta/NXRN1b Antibody [DyLight 550]
Product Specific Notices for Neurexin 1 beta/NXRN1b Antibody [DyLight 550]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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