Neuropilin-2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-86866

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (96%), Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Neuropilin-2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Neuropilin-2 Antibody - BSA Free

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866] - Staining of human skeletal muscle shows weak positivity in myocytes.
Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866] - Staining of human cerebral cortex shows moderate neuropil positivity
Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866] - Staining of human placenta shows moderate membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866]

Immunohistochemistry-Paraffin: Neuropilin-2 Antibody [NBP1-86866] - Staining of human smooth muscle shows moderate positivity.

Applications for Neuropilin-2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
IHC-P reported in scientific literature (PMID: 26199980). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neuropilin-2

NRP2 encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternate Names

Neuropilin2

Entrez Gene IDs

8828 (Human)

Gene Symbol

NRP2

UniProt

O60462 (Human)

Additional Neuropilin-2 Products

Product Documents for Neuropilin-2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Neuropilin-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Neuropilin-2 Antibody - BSA Free

Customer Reviews for Neuropilin-2 Antibody - BSA Free

There are currently no reviews for this product. Be the first to review Neuropilin-2 Antibody - BSA Free and earn rewards!

Have you used Neuropilin-2 Antibody - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Neuropilin-2 Antibody - BSA Free

Showing  1 - 1 of 1 FAQ Showing All

  • Q: Why are the bands shown in the WB different molecular weight? What is the correct size for nrp2? Are they isoforms? I think the dominant one will be 110 KD.

    A:

    It is not the wrong WB image for the NBP1-86866 antibody. This antibody is designed from sequence information in the ENSEMBL database and according to the ENSEMBL database, there is an additional isoform of 62.5 kDa. The antigen of the NBP1-86866 antibody has 100% sequence identity to this isoform as well. The isoform is called NRP2-202 (ENSP00000347238) and consists of 555 amino acids (http://www.ensembl.org/Homo_sapiens/Transcript/Summary?db=core;g=ENSG00000118257;r=2:206547224-206608421;t=ENST00000355117).

Showing  1 - 1 of 1 FAQ Showing All
View all FAQs for Antibodies

Associated Pathways

VEGF - VEGF R2 Signaling Pathways VEGF - VEGF R2 Signaling Pathway Thumbnail