New Products
Discover the latest innovations in research tools from R&D Systems by Bio-Techne. We are committed to continually enhancing and expanding our product portfolio to meet your evolving research needs. Browse our newest releases below, organized by product category. New products can be identified throughout the R&D Systems website by the "New" symbol.
Featured Products
8974 | SALAD1
Ultrabright fluorogenic dye for imaging RNA in live-cells
SALAD1 is a specific and high-affinity aptamer-ligand for aptamer Mango II (KDapp = 0.69 nM). Green fluorogenic dye displaying 3.5-fold brighter fluorescence than other Mango aptamer dyes such as TO1-biotin. Binds 7.5-fold more tightly to Mango II compared to TO dye. SALAD1 exhibits a binding preference to its target RNA (Mango II) over the other three Mango aptamers (7-, 20- and 16-fold tighter than Mango I, III and IV).
The improved brightness and tighter binding of SALAD1 to Mango aptamers allow detection and tracking of RNA with greater sensitivity and spatial resolution, facilitating studies of RNA localization, dynamics, and expression in live-cell and single-molecule imaging applications.