Chemical Name: 4,4'-(Carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid tetrasodium salt
Biological ActivityP2Y11 agonist (pEC50 = 6.27). Exhibits selectivity for P2Y11 over a range of P2Y and P2X receptors.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Citations for NF 546
The citations listed below are publications that use Tocris products. Selected citations for NF 546 include:
2 Citations: Showing 1 - 2
Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells.
Authors: Barragán-Iglesias Et al.
Mol Pain 2014;10:29
The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells.
Authors: Gao Et al.
Sci Adv 2013;9:31
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Used this compound in various concentrations (5-30 uM) to check the cell growth in H69 cells by InCucyte.