Recombinant Human Nicotinic Acetylcholine R alpha 6/CHRNA6 His Protein

Novus Biologicals | Catalog # NBP2-51586

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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all Nicotinic Acetylcholine R alpha 6/CHRNA6 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 26-239 of Human Nicotinic Acetylcholine R alpha 6/CHRNA6

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKGCV GCATEERLFH KLFSHYNQFI RPVENVSDPV TVHFEVAITQ LANVDEVNQI METNLWLRHI WNDYKLRWDP MEYDGIETLR VPADKIWKPD IVLYNNAVGD FQVEGKTKAL LKYNGMITWT PPAIFKSSCP MDITFFPFDH QNCSLKFGSW TYDKAEIDLL IIGSKVDMND FWENSEWEII DASGYKHDIK YNCCEEIYTD ITYSFYIRRL

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

29.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images

SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 6/CHRNA6 His Protein [NBP2-51586]

SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 6/CHRNA6 His Protein [NBP2-51586]

SDS-Page: Nicotinic Acetylcholine R alpha 6/CHRNA6 Recombinant Protein [NBP2-51586] - 15% SDS Page (3 ug)
SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 6/CHRNA6 His Protein [NBP2-51586]

SDS-PAGE: Recombinant Human Nicotinic Acetylcholine R alpha 6/CHRNA6 His Protein [NBP2-51586]

SDS-Page: Nicotinic Acetylcholine R alpha 6/CHRNA6 Recombinant Protein [NBP2-51586] - 15% SDS Page (3 ug)

Formulation, Preparation, and Storage

NBP2-51586
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.4M UREA, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nicotinic Acetylcholine R alpha 6/CHRNA6

Nicotinic acetylcholine receptors (nAChRs, AChRs) are protein complexes made up of protein subunits that coassemble to form an ion channel. This ion channel is gated through the binding of the neurotransmitter acetylcholine (ACh) to its ligand-binding site on the AChR. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA6 (cholinergic nicotinic receptor alpha polypeptide 6) is a neuronal acetylcholine receptor protein.

Long Name

Nicotinic Acetylcholine Receptor alpha 6

Alternate Names

CHRNA6, Nicotinic Acetylcholine Ra6

Gene Symbol

CHRNA6

Additional Nicotinic Acetylcholine R alpha 6/CHRNA6 Products

Product Documents

Certificate of Analysis

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Product Specific Notices

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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