Potassium ionophore, exchanges K+
across biological membranes, in a similar manner to Valinomycin
(Cat. No. 3373). Stimulates mitochondral ATPase activity and disrupts membrane potential. Also acts as an ionophore for Pb2+
with no activity with other divalent cations. Antibiotic derived from Streptomyces hygroscopius
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
The ionophore Nigericin transports Pb2+ with high activity and selectivity: A comparison to Monensin and Ionomycin.
Hamidinia et al.
Energy-linked transhydrogenase: Effects of Valinomycin and Nigericin on the ATP-driven transhydrogenase reaction catalyzed by reconstituted transhydrogenase-ATPase vesicles.
Eytan et al.
The citations listed below are publications that use Tocris products. Selected citations for Nigericin sodium salt include:
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