Nimodipine

  ( 25 citations )    
Product Datasheet
Catalog Number:0600
Chemical Name:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester
Product Details
Citations (25)
Reviews
Biological Activity
L-type Ca2+ channel blocker.
Technical Data
  • M.Wt:
    418.45
  • Formula:
    C21H26N2O7
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    66085-59-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Nimodipine include:

25 Citations: Showing 1 - 10
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  1. Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells.
    Authors: Haeberle Et al.
    Mol Biol Cell  ;3:e1750
  2. Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission.
    Authors: Doshina Et al.
    Sci Rep  2017;7:370
  3. Molecular basis of ancestral vertebrate electroreception.
    Authors: Bellono
    Nature  2017;543:391
  4. Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons.
    Authors: Robinson Et al.
    EMBO J  2015;9:404
  5. Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1.
    Authors: Ciani Et al.
    PLoS One  2015;6:8302
  6. Absence of plateau potentials in dLGN cells leads to a breakdown in retinogeniculate refinement.
    Authors: Dilger Et al.
    J Neurosci  2015;35:3652
  7. Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neurons.
    Authors: Gan and Silverman
    PLoS One  2015;26:1058
  8. Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology.
    Authors: Pourbadie Et al.
    Front Cell Neurosci  2015;10:e0117555
  9. Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds.
    Authors: Schöbel Et al.
    Chem Senses  2014;39:471
  10. Age- and location-dependent differences in store depletion-induced h-channel plasticity in hippocampal pyramidal neurons.
    Authors: Clemens and Johnston
    J Neurophysiol  2014;111:1369
  11. Causes and consequences of hyperexcitation in central clock neurons.
    Authors: Diekman Et al.
    PLoS Comput Biol  2013;9:e1003196
  12. MHCI requires MEF2 transcription factors to negatively regulate synapse density during development and in disease.
    Authors: Elmer Et al.
    J Neurosci  2013;33:13791
  13. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling.
    Authors: Siddoway Et al.
    Br J Pharmacol  2013;33:11206
  14. Optogenetic stimulation of the corticothalamic pathway affects relay cells and GABAergic neurons differently in the mouse visual thalamus.
    Authors: Jurgens Et al.
    PLoS One  2012;7:e45717
  15. Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus.
    Authors: Hulme Et al.
    J Neurosci  2012;32:6785
  16. The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons.
    Authors: Shulga Et al.
    J Neurosci  2012;32:1757
  17. Action potential-independent and pharmacologically unique vesicular serotonin release from dendrites.
    Authors: Colgan Et al.
    J Neurosci  2012;32:15737
  18. Activity-dependent phosphorylation of GABAA receptors regulates receptor insertion and tonic current.
    Authors: Saliba Et al.
    J Neurosci  2012;31:2937
  19. Requirements for synaptically evoked plateau potentials in relay cells of the dorsal lateral geniculate nucleus of the mouse.
    Authors: Dilger Et al.
    J Physiol  2011;589:919
  20. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors.
    Authors: Murray Et al.
    Nat Med  2010;16:694
  21. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors.
    Authors: Higley and Sabatini
    Nat Neurosci  2010;13:958
  22. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.
    Authors: Grey and Burrell
    J Neurophysiol  2010;103:2737
  23. Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity.
    Authors: Wu Et al.
    J Neurophysiol  2008;100:1897
  24. Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex.
    Authors: Bender Et al.
    J Neurosci  2006;26:4166
  25. Molecular profiling reveals synaptic release machinery in Merkel cells.
    Authors: Haeberle Et al.
    Proc Natl Acad Sci U S A  2004;101:14503
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