Catalog Number: 1025
Chemical Name: (±)-γ-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride
Biological Activity
A potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. [3H]Nisoxetine - a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments.
    Cheetham et al.
    Neuropharmacology, 1996;35:63
  2. Norepinephrine transporters in rat placenta labeled with [3H]nisoxetine.
    Shearman and Meyer
    J.Pharmacol.Exp.Ther., 1998;284:736
  3. dl-N-Methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of norepinephrine into rat brain synaptosomes and heart.
    Wong et al.
    Life Sci., 1975;17:755
  4. Down-regulation of norepinephrine transporters on PC12 cells by transporter inhibitors.
    Zhu et al.
    J.Neurochem., 1997;68:134
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