Nisoxetine hydrochloride

Key Product Details

Product Description

Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.

Product Specifications for Nisoxetine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Nisoxetine hydrochloride

The following data is based on the product molecular weight 307.82.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.25 mL	16.24 mL	32.49 mL
5 mM	0.65 mL	3.25 mL	6.50 mL
10 mM	0.32 mL	1.62 mL	3.25 mL
50 mM	0.06 mL	0.32 mL	0.65 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

• Zhu Down-regulation of NE transporters on PC12 cells by transporter inhibitors. J.Neurochem. 1997 PMID: 8978719
• Shearman and Meyer NE transporters in rat placenta labeled with [³H]nisoxetine. J.Pharmacol.Exp.Ther. 1998 PMID: 9454822
• Wong dl-N-Methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of NE into rat brain synaptosomes and heart. Life Sci. 1975 PMID: 1207394
• Cheetham [³H]Nisoxetine - a radioligand for noradrenaline reuptake sites: correlation with inhibition of [³H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments. Neuropharmacology 1996 PMID: 8684598

Product Documents for Nisoxetine hydrochloride