Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2B Clone # 578502
View all NLRP10/Pynod/NALP10 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human NLRP10/Pynod/NALP10
Met386-Ile655
Accession # Q86W26

Specificity

Detects human NLRP10/Pynod/NALP10 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) NALP1 (aa 1‑323), rhNALP1 (aa 1331‑1429), rhNALP2 (aa 1‑208), rhNALP3 (aa 3‑223), rhNALP3 (aa 540‑689), rhNALP5 (aa 469‑635), rhNOD1 (aa 830‑953), or rhNOD2 (aa 230‑450) is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for NLRP10/Pynod/NALP10 Antibody (578502) [Biotin]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NLRP10/Pynod/NALP10

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs tothe NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innateimmune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates thepro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as amultifunctional negative regulator of inflammation and apoptosis. (provided by RefSeq)

Long Name

NLR Family, Pyrin Domain Containing 10

Alternate Names

NALP10, NOD8, PAN5, Pynod

Gene Symbol

NLRP10

Additional NLRP10/Pynod/NALP10 Products

Product Documents for NLRP10/Pynod/NALP10 Antibody (578502) [Biotin]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for NLRP10/Pynod/NALP10 Antibody (578502) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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