Chemical Name: 1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea
Biological ActivityNNC 26-9100 is a somatostatin sst4 receptor agonist that displays > 100-fold selectivity over sst2 receptors (Ki values are 6 and 621 nM for sst4 and sst2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC50 = 26 nM).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Nonpeptide somatostatin agonists with sst4 selectivity: synthesis and structure-activity relationships of thioureas.
Liu et al.
2-pyridylthioureas: novel nonpeptide somatostatin agonists with SST4 selectivity.
Liu et al.
Citation for NNC 26-9100
The citations listed below are publications that use Tocris products. Selected citations for NNC 26-9100 include:
1 Citation: Showing 1 - 1
Inhibitory effect of somatostatin receptor subtype-4 agonist NNC 26-9100 on micturition reflex in rats.
Authors: Honda Et al.
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