NNC 711

Catalog # Availability Size / Price Qty
1779/10
1779/50
NNC 711 | CAS No. 145645-62-1 | GABA Transporter Inhibitors
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Description: Selective GAT-1 inhibitor

Chemical Name: 1,2,5,6-Tetrahydro-1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-3-pyridinecarboxylic acid hydrochloride

Purity: ≥99%

Product Details
Citations (4)
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Biological Activity

Potent and selective inhibitor of GABA uptake by GAT-1 (IC50 values are 0.04, 171, 1700 and 622 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo. Also exhibits cognition-enhancing activity.

Technical Data

M.Wt:
386.88
Formula:
C21H22N2O3.HCl
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
145645-62-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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