NOD2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-27118

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Monkey (95%), Primate (97%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot, Immunoprecipitation

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all NOD2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids 125-162 of human Nod2.

Reactivity Notes

The amino acid sequence used as immunogen is 95% homologous in Lar gibbon (Hylobates lar), 97% in chimpanzee.

Specificity

Researchers are encouraged to optimize dilutions for their specific testing, and to use the sequence information and accession number (NP_071445.1/Q9HC29) that was used to design the peptide immunogen in order to assess potential cross-reactivity of the antibody.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for NOD2 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole sera with 50% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NOD2

Apaf-1 and Nod1 are members of a protein family, each of which contains a caspase recruitment domain (CARD) linked to a nucleotide-binding domain, which regulate apoptosis and/or NF-kB activation. Recently, Nod2, a third member of the family has been identified. Recent studies indicate that Nod2 activates NF-kB, but unlike Nod1, this new homologue is primary expressed in monocytes.

Alternate Names

BLAU, CARD15caspase recruitment domain protein 15, caspase recruitment domain family, member 15, Caspase recruitment domain-containing protein 15, CDACUG, CLR16.3, IBD1NLR family, CARD domain containing 2, Inflammatory bowel disease protein 1, NLRC2, NOD-like receptor C2, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain containing 2, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domaincontaining 2, nucleotide-binding oligomerization domain-containing protein 2, PSORAS1NOD2B

Gene Symbol

NOD2

UniProt

Q9HC29 (Human)

Additional NOD2 Products

Product Documents for NOD2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for NOD2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for NOD2 Antibody - BSA Free

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FAQs for NOD2 Antibody - BSA Free

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  • Q: Can you suggest the best NOD2 antibody for detection of endogenous NOD2 in human fibroblasts?

    A: For detecting endogenous NOD2 in human samples, I would recommend NB100-524. This antibody has been validated for use in WB, IHC-Paraffin and IP.

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