NS 9283

   
Product Datasheet
Catalog Number:5112
Chemical Name:3-[3-(3-Pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
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Biological Activity
Positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ~60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells). Reduces the rate of recovery from desensitization and slows the rate of deactivation. Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.
Technical Data
  • M.Wt:
    248.24
  • Formula:
    C14H8N4O
  • Solubility:
    Soluble to 50 mM in DMSO and to 20 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    913830-15-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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