NU 9056

  ( 3 citations )    
Product Datasheet
Catalog Number:4903
Chemical Name:5-(1,2-Thiazol-5-yldisulfanyl)-1,2-thiazole
Product Details
Citations (3)
Reviews
Biological Activity
Selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.
Technical Data
  • M.Wt:
    232.37
  • Formula:
    C6H4N2S4
  • Solubility:
    Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)
  • Storage:
    Store at -20°C
  • CAS No:
    1450644-28-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for NU 9056 include:

3 Citations: Showing 1 - 3
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  1. Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion.
    Authors: Bakshi Et al.
    Sci Rep  2017;7:3635
  2. Novel detection of post-translational modifications in human monocyte-derived dendritic cells after chronic alcohol exposure: Role of inflammation regulator H4K12ac.
    Authors: Parira Et al.
    Sci Rep  2017;7:11236
  3. Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.
    Authors: Rollins Et al.
    PLoS Genet  2017;13:e1006626

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