Orlistat

Catalog # Availability Size / Price Qty
3540/10
3540/50
Orlistat | CAS No. 96829-58-2 | Lipase Inhibitors
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Description: Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity

Chemical Name: N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester

Purity: ≥99%

Product Details
Citations (5)
Reviews

Biological Activity

Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A2, liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G1/S boundary in vitro. Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo.

Technical Data

M.Wt:
495.73
Formula:
C29H53NO5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
96829-58-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Orlistat

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