2 results for "Fatty Acid Synthase Inhibitors" in Products

Fatty Acid Synthase Inhibitors

Fatty acid synthase (FASN), EC 2.3.1.85, catalyzes the final stage of de novo fatty acid (FA) synthesis, that is the conversion of acetyl-CoA and malonyl-CoA to the 16-carbon FA palmitate. FASN is a multienzyme, exhibiting the catalytic properties required for palmitate synthesis including synthase, transferase, dehydrase, reductase and thioesterase activity, in addition to NADPH binding.

Expression and activity levels of FASN in normal tissues are typically low, being highest in ...

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Potent fatty acid synthase inhibitor; proapoptotic

Alternate Names: trans-C 75
Chemical Name: (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid
Purity: ≥94%
Potent fatty acid synthase inhibitor; proapoptotic
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Potent human fatty acid synthase (hFASN) inhibitor

Chemical Name: 4-[4-(5-Benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
Purity: ≥98%
Potent human fatty acid synthase (hFASN) inhibitor
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