Chemical Name: 10,11-Dihydro-10-oxo-5H-dibenzo(Z)[b,f]azepine-5-carboxamide
Biological ActivityOxcarbazepine is an anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action.
Schmutz et al.
Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures.
Zheng et al.
Mechanism of action of carbamaz. and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.
Ambrosio et al.
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