Anticonvulsant; protects mice and rats against generalized tonic-clonic seizures induced by electroshock. Thought to act via inhibition of sodium channel activity.
Soluble to 50 mM in DMSO
Store at RT
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All Tocris products are intended for laboratory research use only.
Oxcarbazepine: preclinical anticonvulsant profile and putative mechanism of action.
Schmutz et al.
Oxcarbazepine, not its active metabolite, potentiates GABAA activation and aggravates absence seizures.
Zheng et al.
Mechanism of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024.
Ambrosio et al.