Licarbazepine

Catalog # Availability Size / Price Qty
3865/10
3865/50
Licarbazepine | CAS No. 29331-92-8 | Voltage-gated Sodium Channel Inhibitors
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Description: Active metabolite of oxcarbazepine (Cat. No. 3864)
Alternative Names: GP 47779

Chemical Name: 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

Active metabolite of oxcarbazepine (Cat. No. 3864). Produces dose-dependent inhibition of glutamatergic excitatory postsynaptic potentials (EPSPs). Displays anticonvulsant activity; exhibits minor potentiation of GABAA receptor currents.

Technical Data

M.Wt:
254.28
Formula:
C15H14N2O2
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
29331-92-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Inhibiting currents through Nav1.5 voltage gated sodium channel
By Theresa Leslie on 05/08/2020
Application: Species: Human

Inhibiting currents through voltage gated sodium channel Nav1.5 in HEK-293-Nav1.5 cells. We used it at a concentration of 300 micromolar.


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