Licarbazepine

Tocris Bioscience | Catalog # 3865

Active metabolite of oxcarbazepine (Cat. No. 3864)
Tocris Bioscience

Key Product Details

Description

Active metabolite of oxcarbazepine (Cat. No. 3864)

Alternative Names

GP 47779
View all Voltage-gated Sodium Channel Inhibitors »

Product Description

Licarbazepine is an active metabolite of oxcarbazepine (Cat. No. 3864). Produces dose-dependent inhibition of glutamatergic excitatory postsynaptic potentials (EPSPs). Displays anticonvulsant activity; exhibits minor potentiation of GABAA receptor currents.

Product Specifications for Licarbazepine

Molecular Weight

254.28

Formula

C15H14N2O2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide

CAS Number

29331-92-8

PubChem ID

114709

InChI Key

BMPDWHIDQYTSHX-UHFFFAOYSA-N

SMILES

NC(N2C1=CC=CC=C1C(O)CC3=C2C=CC=C3)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25.43 100

Preparing Stock Solutions for Licarbazepine

The following data is based on the product molecular weight 254.28.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.93 mL 19.66 mL 39.33 mL
5 mM 0.79 mL 3.93 mL 7.87 mL
10 mM 0.39 mL 1.97 mL 3.93 mL
50 mM 0.08 mL 0.39 mL 0.79 mL

Calculators

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Product Documents for Licarbazepine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Licarbazepine

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for Licarbazepine (1)

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  • Inhibiting currents through Nav1.5 voltage gated sodium channel
    Name: Theresa Leslie
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK293-Nav1.5
    Verified Customer | Posted 05/08/2020
    A stock solution of 100 mM in DMSO was used.
    Inhibiting currents through voltage gated sodium channel Nav1.5 in HEK-293-Nav1.5 cells. We used it at a concentration of 300 micromolar.
    Licarbazepine 3865

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