PACE4/PCSK6 Antibody - BSA Free

Novus Biologicals | Catalog # NB110-55609

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rabbit

Predicted:

Monkey (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PACE4/PCSK6 Primary Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from internal region of human PACE4/PCSK6.

Epitope

internal domain of human protein

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Mouse (88%), Rat (88%), Bovine (88%), Canine (88%), Equine (88%), Porcine (88%), Opossum (88%), Bat (81%).

Specificity

Human PACE4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PACE4/PCSK6 Antibody - BSA Free

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody - BSA Free [NB110-55609]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody - BSA Free [NB110-55609]

Immunohistochemistry-Paraffin: PACE4 Antibody [NB110-55609] - Analysis of anti-PACE4 antibody with human brain, cortex.

Applications for PACE4/PCSK6 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 - 15 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

0.7 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PACE4/PCSK6

PACE4 is a Serine S8 type protease that cleaves precursor proteins at paired basic amino acid processing sites. Several PACE4 substrates have been identified, including transforming growth factor beta-related proteins, proalbumin and von Willebrand factor. At least eight alternatively spliced transcript variants encoding different isoforms have been reported. In mouse, PACE4 has been shown to increase tumor cell invasiveness, and thus enhance tumor progression.

Long Name

Proprotein Convertase Subtilisin/Kexin Type 6

Alternate Names

PACE4, PCSK6, Proprotein Convertase 6, SPC4

Entrez Gene IDs

5046 (Human)

Gene Symbol

PCSK6

Additional PACE4/PCSK6 Products

Product Documents for PACE4/PCSK6 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PACE4/PCSK6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Serine Proteases and Regulators

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Protocols

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FAQs

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