Atypical antipsychotic; metabolite of risperidone
(Cat. No. 2865). Exhibits high affinity for 5-HT2A
= 0.4 nM for cloned human 5-HT2A
receptors). Also displays nanomolar affinity for human D2
Soluble to 10 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.
Leysen et al.
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.
Schotte et al.
Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons.
Dremencov et al.
In vivo pharmacological profile of 9-hydroxyrisperidone, the major metabolite of the novel antipsychotic risperidone.
Megens and Awouters et al.