PAMP-20 (human)

Catalog # Availability Size / Price Qty
6552/1
Cat.No. 6552 - PAMP-20 (human) | Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2 | CAS No. 150238-87-2
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Description: MRGPRX2 agonist
Product Details
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Biological Activity

Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.

Technical Data

M.Wt:
2460.87
Formula:
C112H178N36O27
Sequence:
ARLDVASEFRKKWNKWALSR

(Modifications: Arg-20 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
150238-87-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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