PAMP-20 (human)

   
Product Datasheet
Catalog Number:6552
Chemical Name:
Product Details
Reviews
Biological Activity
Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 - 20 of proadrenomedullin. Antihypertensive.
Technical Data
  • M.Wt:
    2460.87
  • Formula:
    C112H178N36O27
  • Sequence:
    ARLDVASEFRKKWNKWALSR

    (Modifications: Arg-20 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    150238-87-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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