PAX8 Antibody (RM436)

Novus Biologicals | Catalog # NBP3-18831

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM436 expressed in HEK293
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Product Specifications

Immunogen

A peptide corresponding to the C-terminus of PAX8 (Uniprot # Q06710)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PAX8 Antibody (RM436)

PAX8 Antibody (RM436)

Immunohistochemistry: PAX8 Antibody (RM436)[NBP3-18831]

Immunohistochemistry: PAX8 Antibody (RM436)[NBP3-18831]Immunohistochemical staining of formalin fixed and paraffin embedded human Kidney tissue section using anti-Paired box protein Pax-8 rabbit monoclonalantibody (Clone RM436) at a 1:400 dilution.
PAX8 Antibody (RM436)

Immunohistochemistry-Paraffin: PAX8 Antibody (RM436) [NBP3-18831] -

Immunohistochemistry-Paraffin: PAX8 Antibody (RM436) [NBP3-18831] - Immunohistochemical staining of formalin fixed and paraffin embedded human thyroid tissue section using RM436 at a 1:400 dilution.

Applications for PAX8 Antibody (RM436)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:400

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: PAX8

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described.

Alternate Names

paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8

Gene Symbol

PAX8

Additional PAX8 Products

Product Documents for PAX8 Antibody (RM436)

Certificate of Analysis

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Product Specific Notices for PAX8 Antibody (RM436)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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