PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1)

Novus Biologicals | Catalog # NBP3-19490

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-2A1 expressed in HEK293
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Product Specifications

Immunogen

A synthetic peptide of human PD-L2/B7-DC/PDCD1LG2 (Uniprot # Q9BQ51)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1)

Western Blot: PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1) [NBP3-19490]

Western Blot: PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1) [NBP3-19490]

Western Blot: PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1) [NBP3-19490] - Western blot detection of PD-L2/B7-DC/PDCD1LG2 in K562, C6 cell lysates using NBP3-19490 (1:1000 diluted). Predicted band size: 31kDa. Observed band size: 31kDa.

Applications for PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PD-L2/B7-DC

B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. B7-DC (CD273) has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. B7-DC (CD273) has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Long Name

Programmed Death-1 Ligand-2

Alternate Names

B7-DC, Butyrophilin-like Protein, CD273, PDCD1LG2, PDL2

Gene Symbol

PDCD1LG2

Additional PD-L2/B7-DC Products

Product Documents for PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PD-L2/B7-DC/PDCD1LG2 Antibody (S02-2A1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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