Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

DyLight 350 (Excitation = 353 nm, Emission = 432 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 184805
View all PDGF-AA Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant rat PDGF‑AA
Ser87-Arg196
Accession # AAB59693

Specificity

Detects rat PDGF-AA in direct ELISAs and Western blots. In direct ELISAs, 5‑35% cross‑reactivity with recombinant rat (rr) PDGF-AB, recombinant human (rh) PDGF-AA, and rhPDGF-AB is observed and no cross-reactivity with rrPDGF-BB, rhPDGF-BB, or rhPDGF-CC is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for PDGF-AA Antibody (184805) [DyLight 350]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PDGF-AA

PDGF-AA (Platelet-Derived Growth Factor AA) is a widely expressed protein that forms disulfide linked homodimers or heterodimers with PDGF-B. PDGF-AA is expressed by monocytes, macrophages, fibroblasts, vascular smooth muscle cells, and vascular endothelial cells. It acts principally as a chemoattractant and inducer of protein synthesis in multiple cell types. PDGF-AA binds and signals through homodimers of the receptor tyrosine kinase PDGF R alpha which itself associates with FGF R1 and Neuropilin-1. PDGF-AA additionally signals through heterodimers of PDGF R alpha and PDGF R beta.

Long Name

Platelet-derived Growth Factor AA

Alternate Names

PDGFAA

Gene Symbol

PDGFA

Additional PDGF-AA Products

Product Documents for PDGF-AA Antibody (184805) [DyLight 350]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for PDGF-AA Antibody (184805) [DyLight 350]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

PDGF Family

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