Pepstatin A

Tocris Bioscience | Catalog # 1190

Selective and high affinity cathepsin D inhibitor
Tocris Bioscience

Key Product Details

Description

Selective and high affinity cathepsin D inhibitor
View all Additional Synthetic Protease Inhibitors »

Product Description

Pepstatin A is an irreversible inhibitor of aspartic proteases. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with E 64d (Cat. No. 4545).

Product Specifications for Pepstatin A

Molecular Weight

685.91

Formula

C34H63N5O9

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

26305-03-3

PubChem ID

5478883

InChI Key

FAXGPCHRFPCXOO-LXTPJMTPSA-N

SMILES

O=C(N[C@@H](CC(C)C)[C@@H](O)CC(N[C@@H](C)C(N[C@H]([C@@H](O)CC(O)=O)CC(C)C)=O)=O)[C@H]([C@@H](C)C)NC([C@@H](NC(CC(C)C)=O)C(C)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in Ethanol with gentle warming

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 42 publications citing the usage of this product.

Product Documents for Pepstatin A

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pepstatin A

For research use only

Customer Reviews for Pepstatin A (5)

4.6 out of 5
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  • Pepstatin A
    Name: Caterina Suelzu
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: MCF7 cells
    Verified Customer | Posted 01/31/2025
    1mM used in cell lysate for Western Blot
    Pepstatin A 1190
  • Pepstatin A
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HCT116
    Verified Customer | Posted 01/28/2025
    Protease inhibition in cell lysates 1 mM, samples subjected to Western Blot
    Pepstatin A 1190
  • Pepstatin A
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 11/11/2024
    Used to make up a lysis buffer for an ELISA (DYC1047-2), worked well.
  • good performance
    Name: Estela Correa
    Species: Mouse
    Assay Type: Ex Vivo
    Verified Customer | Posted 07/27/2022
    Leave in a container to prevent exposure to moisture.
    1:1000. Performed ideally
  • Protease Inhibitor
    Name: Reetu Singh
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Vessels
    Verified Customer | Posted 03/08/2021
    use this as a protease inhibitor in my protein isolation buffer. It was a beneficial product for the Rat profiling cytokine assay kit.
    Pepstatin A 1190

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