E 64d

Catalog # Availability Size / Price Qty
4545/1
E 64d | CAS No. 88321-09-9 | Synthetic Cathepsin Inhibitors
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Description: Cathepsin inhibitor; interferes with autolysosomal digestion

Chemical Name: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester

Purity: ≥98%

Product Details
Citations (2)
Reviews

Biological Activity

Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. No. 1190). Lysosome and cell permeable. Also inhibits entry of SARS-Cov-2 (COVID-19) into Caco-2 and Vero cells in combination with Camostat mesylate (Cat.No. 3193) in vitro.

Technical Data

M.Wt:
342.43
Formula:
C17H30N2O5
Solubility:
Soluble to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
88321-09-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for E 64d

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