Human Peroxiredoxin 6 ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) CV% 6.1 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) CV% 10.8 (example only; lot dependent)

Recovery for Human Peroxiredoxin 6 ELISA Kit (Colorimetric)

Scientific Data Images for Human Peroxiredoxin 6 ELISA Kit (Colorimetric)

Preparation and Storage

Background: Peroxiredoxin 6

FUNCTION: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. SUBUNIT: Homotetramer. May interact with HTR2A. SUBCELLULAR LOCATION: Cytoplasm. Lysosome. Note=Also found in lung secretory organelles. MISCELLANEOUS: The active site is the redox-active Cys-47 oxidized to Cys-SOH. Cys-SOH may rapidly react with a Cys-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin. MISCELLANEOUS: Irreversibly inactivated by overoxidation of Cys-47 (to Cys-SO(3)H) upon oxidative stress. SIMILARITY: Belongs to the ahpC/TSA family. Rehydrin subfamily.

Additional Peroxiredoxin 6 Products

• All Products for Peroxiredoxin 6
• Peroxiredoxin 6 cDNA Clones
• Peroxiredoxin 6 ELISA Kits
• Peroxiredoxin 6 Lysates
• Peroxiredoxin 6 Primary Antibodies
• Peroxiredoxin 6 Proteins and Enzymes

Product Documents for Human Peroxiredoxin 6 ELISA Kit (Colorimetric)