Selective casein kinase 1ε
inhibitor; displays 22-fold greater potency towards CK1ε
values are 32 and 711 nM for CK1ε
respectively). ATP competitive. Displays minimal effect on the circadian clock.
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Selective inhibition of casein kinase 1ε minimally alters circadian clock period.
Walton et al.
Casein kinase 1 delta (CK1δ) regulates period length of the mouse suprachiasmatic circadian clock in vitro.
Etchegaray et al.
PLoS One, 2010;5:e10303
Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes.
Meng et al.
The citations listed below are publications that use Tocris products. Selected citations for PF 4800567 hydrochloride include:
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