Phenamil

Catalog # Availability Size / Price Qty
3379/10
3379/50
Cat.No. 3379 - Phenamil | C12H12ClN7O.CH3SO3H | CAS No. 1161-94-0
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Description: Inhibits TRPP3-mediated currents; also inhibits epithelial Na+ channels

Chemical Name: 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt

Purity: ≥99%

Product Details
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Biological Activity

TRPP3 channel inhibitor (IC50 = 0.14 μM). Also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Derivative of amiloride (Cat. No. 0890).

Technical Data

M.Wt:
401.83
Formula:
C12H12ClN7O.CH3SO3H
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1161-94-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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