PIEZO2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89893

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ESEKPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKM

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PIEZO2 Antibody - BSA Free

PIEZO2 Antibody - BSA Free Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
PIEZO2 Antibody - BSA Free Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Staining of human cervix, uterine shows no positivity in squamous epithelial cells as expected.
PIEZO2 Antibody - BSA Free Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Staining of human colon shows weak cytoplasmic positivity in glandular cells.
PIEZO2 Antibody - BSA Free Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Immunohistochemistry-Paraffin: PIEZO2 Antibody - BSA Free [NBP1-89893]

Staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.

Applications for PIEZO2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIEZO2

Coming from the Greek ''piesi'' and meaning "pressure", PIEZO2 is integral to the membrane and is involved in ion channel activity, cation channel activity and the regulation of membrane potential. Having between 24 and 36 transmembrane domains, PIEZO's are big transmembrane proteins found in a variety of species. More specifically, PIEZO2 is required for rapidly adapting mechanically activated current in somatosensory and DRG neurons.

Long Name

PIEZO2

Alternate Names

C18orf30, C18orf58, DA3, DA5, DAIPT, FAM38B, FAM38B2, family with sequence similarity 38, member A pseud, family with sequence similarity 38, member B2, HsT748, HsT771, MWKS, piezo-type mechanosensitive ion channel component

Gene Symbol

PIEZO2

Additional PIEZO2 Products

Product Documents for PIEZO2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PIEZO2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for PIEZO2 Antibody - BSA Free

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  • Q: In my project we need Anti Piezo2 and we find it in your catalogs. PIEZO2 Antibody. I want to know the prediction size of your antibody. The size of the protein is more than 200 kd. but in this photo there there are some sharp band are there the actual bands?

    A: The predicted molecular weights for this protein are based on the multiple transcripts associated with this protein. Please see Ensembl for detailed information. Those expected molecular weights are the following: 318.1, 80.8, 73.8, 62.7 kDa. We see this kind of staining across many of our antibodies for PIEZO2. It would appear that the transcript present is dependent on the tissue type. Based on protein arrays, we do believe that this antibody is specific.

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