PMP22 Antibody (JM52-30)

Novus Biologicals | Catalog # NBP2-67068

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # JM52-30 expressed in HEK293
View all PMP22 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide within Human PMP22 aa 1-50 / 160. (SwissProt: Q01453 Human; SwissProt: P16646 Mouse; SwissProt: P25094 Rat)

Localization

Cell membrane.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PMP22 Antibody (JM52-30)

Western Blot: PMP22 Antibody (JM52-30) [NBP2-67068]

Western Blot: PMP22 Antibody (JM52-30) [NBP2-67068]

Western Blot: PMP22 Antibody (JM52-30) [NBP2-67068] - Western blot analysis of PMP22 on PC-12 cell lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:5,000 dilution was used for 1 hour at room temperature.

Applications for PMP22 Antibody (JM52-30)

Application
Recommended Usage

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

TBS (pH7.4), 0.05% BSA, 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PMP22

Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).

Alternate Names

CMT1A, CMT1E, GAS3, GAS-3DSS, growth arrest-specific 3, Growth arrest-specific protein 3, HMSNIA, HNPP, MGC20769, peripheral myelin protein 22, PMP-22, Sp110

Gene Symbol

PMP22

Additional PMP22 Products

Product Documents for PMP22 Antibody (JM52-30)

Certificate of Analysis

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Product Specific Notices for PMP22 Antibody (JM52-30)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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