PNRC2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-74252

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PNRC2 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to the N terminal of Pnrc2. Immunizing peptide sequence MGGGERYNIPDPQSRNASKNQQQHNRQKTKDQNSQMKIVHKKKERGHGYN. The peptide sequence for this immunogen was taken from within the described region.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 28821679).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PNRC2 Antibody - BSA Free

Western Blot: PNRC2 Antibody [NBP1-74252]

Western Blot: PNRC2 Antibody [NBP1-74252]

Western Blot: PNRC2 Antibody [NBP1-74252] - Rat Kidney Lysate 1ug/ml Gel Concentration 10-20%

Applications for PNRC2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PNRC2

Pnrc2 is involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. It may act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. It is required for UPF1/RENT1 localization to the P-body.It also acts as a nuclear receptor coactivator. It may play a role in controlling the energy balance between energy storage and energy expenditure.

Alternate Names

proline-rich nuclear receptor coactivator 2

Gene Symbol

PNRC2

UniProt

Q66HE1 (Rat)

Additional PNRC2 Products

Product Documents for PNRC2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PNRC2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PNRC2 Antibody - BSA Free

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FAQs

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