PNU 282987

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2303/10
2303/50
PNU 282987 | CAS No. 711085-63-1 | Nicotinic (a7) Receptor Agonists
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Description: Selective α7 nAChR agonist

Chemical Name: N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide

Purity: ≥98%

Product Details
Citations (3)
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Biological Activity

Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).

Technical Data

M.Wt:
264.75
Formula:
C14H17ClN2O
Solubility:
Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
711085-63-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for PNU 282987

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