Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Sheep IgG
View all PP2C beta/PPM1B Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human PP2C beta
Met1-Gly378
Accession # O75688

Specificity

Detects endogenous human, mouse and rat PP2C beta in Western blots. In Western blots, this antibody does not cross‑react with recombinant human PP2C alpha or PP2C delta.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for PP2C beta/PPM1B Antibody [PE]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PP2C beta/PPM1B

PPM1B is encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Long Name

Protein Phosphatase 2C beta

Alternate Names

Pp2c2, PP2CB, PPM1B

Gene Symbol

PPM1B

Additional PP2C beta/PPM1B Products

Product Documents for PP2C beta/PPM1B Antibody [PE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for PP2C beta/PPM1B Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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