PP2C beta/PPM1B Antibody

Novus Biologicals | Catalog # NB110-38886

Novus Biologicals
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all PP2C beta/PPM1B Primary Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 450 and the C-terminus (residue 479) of human Protein Phosphatase 1B, Magnesium-Dependent, Beta Isoform using the numbering given in entry NP_002697.1 (GeneID 5495).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PP2C beta/PPM1B Antibody

Western Blot: PP2C beta/PPM1B Antibody [NB110-38886]

Western Blot: PP2C beta/PPM1B Antibody [NB110-38886]

Western Blot: PP2C beta/PPM1B Antibody [NB110-38886] - PPM1B Antibody [NB110-38886] - Detection of Human and Mouse PPM1B on HeLa whole cell lysate using NB110-38886. PPM1B was also immunoprecipitated by rabbit anti-PPM1B antibody NB110-38885.

Applications for PP2C beta/PPM1B Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PP2C beta/PPM1B

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences

Long Name

Protein Phosphatase 2C beta

Alternate Names

Pp2c2, PP2CB, PPM1B

Entrez Gene IDs

5495 (Human)

Gene Symbol

PPM1B

UniProt

NP_002697.1 (Human)

Additional PP2C beta/PPM1B Products

Product Documents for PP2C beta/PPM1B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PP2C beta/PPM1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PP2C beta/PPM1B Antibody

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