Probenecid

  ( 2 citations )    
Product Datasheet
Catalog Number:4107
Chemical Name:4-(Dipropylsulfamoyl)benzoic acid
Product Details
Citations (2)
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Biological Activity
Inhibitor of multidrug resistance-associated proteins (MRP). Inhibits organic acid transport in the kidney and other organs. Also exhibits inhibitory activity against pannexin 1 channels (IC50 ~ 150 μM).
Technical Data
  • M.Wt:
    285.36
  • Formula:
    C13H19NO4S
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    57-66-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Probenecid include:

2 Citations: Showing 1 - 2
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  1. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation.
    Authors: Ostrovskaya Et al.
    J Biomed Sci  2014;21:74
  2. C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation.
    Authors: Asgari Et al.
    J Biol Chem  2013;122:3473

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