Prostaglandin E Synthase Antibody - BSA Free

Novus Biologicals | Catalog # NB110-39058

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rat, Porcine, Bovine, Canine, Chicken, Equine, Monkey, Primate, Rabbit, Zebrafish

Predicted:

Avian (100%), Fish (100%), Opossum (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Synthetic 14 aa peptide from near N-terminus of human Prostaglandin E Synthase.

Epitope

near N-terminus of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Platypus, Pufferfish, Stickleback (100%), Pike (93%).

Specificity

Human PTGES. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Prostaglandin E Synthase Antibody - BSA Free

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody - BSA Free [NB110-39058]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody - BSA Free [NB110-39058]

Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody - BSA Free [NB110-39058] - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

Applications for Prostaglandin E Synthase Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

10 - 20 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Prostaglandin E Synthase

PGES-1 is a membrane associated protein involved in eicosanoid and glutathione metabolism as part of the arachidonic acid signaling pathway. The expression of this protein is induced by the proinflammatory cytokine IL-1B and its' activity is glutathione dependent. PGES is also expressed at high levels in P53 expressing cells.

Long Name

Prostaglandin E synthase

Alternate Names

EC 5.3.99.3, MGST1-L1, MGST1L1, MPGES-1, MPGES1, PGES, PIG12, PTGES

Entrez Gene IDs

9536 (Human)

Gene Symbol

PTGES

Additional Prostaglandin E Synthase Products

Product Documents for Prostaglandin E Synthase Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Prostaglandin E Synthase Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Prostaglandin E Synthase Antibody - BSA Free

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  • Q: I am looking to use this antibody (PTGES NB110-39058) on opossum - Monodelphis domestica - for both Immunohistochemistry in paraffin embedded tissues and in western blotting. I was hoping that you could provide me with a more specific amino acid sequence to Blast. Does the percentage in parentheses next to Opossum on the datasheet indicate the homology between the antibody sequence and that of opossum when aligned?

    A:

    The 100% homology does refer to the immunogen sequence and the opossum sequence of the 14 amino acids. I am afraid we do not have access to the actual sequence since the inventor holds the information as proprietary. This antibody has not been validated in western blot but it is guaranteed to work in IHC-P. Our Innovator’s Reward™ program was created to allow researchers the opportunity to try our primary antibodies in an untested species or application, without the financial risk of failure. To participate you simply purchase the product as normal and submit an online review detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product to use in a future purchase of your choice. Reviews may also be submitted by emailing innovators@novusbio.com.

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