Chemical Name: 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt
Biological ActivityProstaglandin E2 and F2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.
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Prostaglandins and throboxanes.
Samuelsson et al.
Involvement of endothelin-1 and its receptors in PGF2α-induced luteolysis in the rat.
Girsh and Dekel
Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo.
Lai et al.
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