Prostaglandin F_2α

Name: Prostaglandin F 2α
Brand: Tocris Bioscience
SKU: 4214
Price: 353 USD
Availability: InStock

Tocris Bioscience | Catalog # 4214

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Citations (2)

Product Documents

Naturally-occurring prostanoid; potent vasoconstrictor

Product Description
Product Specifications
Solubility
Preparing Stock Solutions
Calculators
Background References
Product Documents
Specific Notices
Research Areas

Key Product Details

Description

Naturally-occurring prostanoid; potent vasoconstrictor

View all Prostanoid Receptor Agonists »

Product Description

Prostaglandin F_2α is a prostaglandin E₂ and F_2α receptor agonist. Naturally-occurring prostaglandin and potent vasoconstrictor. Induces cardiomyocyte hypertrophy in vitro. Exhibits luteolytic activity.

Product Specifications for Prostaglandin F_2α

Molecular Weight

475.62

Formula

C₂₀H₃₄O₅.C₄H₁₁NO₃

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt

CAS Number

38562-01-5

PubChem ID

5282415

InChI Key

IYGXEHDCSOYNKY-RZHHZEQLSA-N

SMILES

O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.NC(CO)(CO)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	47.56	100
	Ethanol	47.56	100

Preparing Stock Solutions for Prostaglandin F_2α

The following data is based on the product molecular weight 475.62.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.10 mL	10.51 mL	21.03 mL
5 mM	0.42 mL	2.10 mL	4.21 mL
10 mM	0.21 mL	1.05 mL	2.10 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Calculators

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Mass

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Background References

References are publications that support the biological activity of the product.

Girsh and Dekel Involvement of endothelin-1 and its receptors in PGF_2α-induced luteolysis in the rat. Mol.Reprod.Dev. 2002 PMID: 12211063
Lai Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Am.J.Physiol.
Samuelsson Prostaglandins and throboxanes. Annu.Rev.Biochem. 1978 PMID: 209733

Product Documents for Prostaglandin F_2α

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Prostaglandin F_2α

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Eicosanoids and Regulators

Citations for Prostaglandin F_2α

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