PSD-95 Antibody - Azide Free

Novus Biologicals | Catalog # NB300-294

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Bovine (100%), Human (100%), Primate (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide Free
View all PSD-95 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. Accession # P31016

Reactivity Notes

It is anticipated that the antibody will also work with bovine, human, non-human primates and zebra fish tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.

Localization

Cytoplasmic

Marker

post-Synaptic Marker

Specificity

Specific for endogenous levels of the ~95 kDa PSD-95 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

95 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PSD-95 Antibody - Azide Free

Western Blot: PSD-95 Antibody [NB300-294]

Western Blot: PSD-95 Antibody [NB300-294]

Western Blot: PSD-95 Antibody [NB300-294]

Applications for PSD-95 Antibody - Azide Free

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Format

Azide Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PSD-95

PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other protein in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses. Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation.

Long Name

Postsynaptic Density Protein 95/Disks Large Homolog 4

Alternate Names

DLG4, PSD95, SAP90

Entrez Gene IDs

1742 (Human); 13385 (Mouse); 29495 (Rat)

Gene Symbol

DLG4

UniProt

P31016 (Rat)

Additional PSD-95 Products

Product Documents for PSD-95 Antibody - Azide Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PSD-95 Antibody - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PSD-95 Antibody - Azide Free

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FAQs

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