PXR/NR1I2 Antibody (6H11D8) - BSA Free

Novus Biologicals | Catalog # NBP2-61817

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6H11D8

Format

BSA Free
View all PXR/NR1I2 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human PXR/NR1I2 (AA:1-142) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PXR/NR1I2 Antibody (6H11D8) - BSA Free

Western Blot: PXR/NR1I2 Antibody (6H11D8)BSA Free [NBP2-61817]

Western Blot: PXR/NR1I2 Antibody (6H11D8)BSA Free [NBP2-61817]

Western Blot: PXR/NR1I2 Antibody (6H11D8) [NBP2-61817] - Analysis using NR1I2 mAb against human NR1I2 (AA: 1-142) recombinant protein. (Expected MW is 42.2 kDa)
Western Blot: PXR/NR1I2 Antibody (6H11D8)BSA Free [NBP2-61817]

Western Blot: PXR/NR1I2 Antibody (6H11D8)BSA Free [NBP2-61817]

Western Blot: PXR/NR1I2 Antibody (6H11D8) [NBP2-61817] - Analysis using NR1I2 mAb against HEK293 (1) and NR1I2 (AA: 1-142)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA: PXR/NR1I2 Antibody (6H11D8) - BSA Free [NBP2-61817]

ELISA: PXR/NR1I2 Antibody (6H11D8) - BSA Free [NBP2-61817]

ELISA: PXR/NR1I2 Antibody (6H11D8) [NBP2-61817] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
ELISA: PXR/NR1I2 Antibody (6H11D8) - BSA Free [NBP2-61817]

ELISA: PXR/NR1I2 Antibody (6H11D8) - BSA Free [NBP2-61817]

ELISA: PXR/NR1I2 Antibody (6H11D8) [NBP2-61817] - Analysis of HepG2 cells using NR1I2 mouse mAb (green) and negative control (red).

Applications for PXR/NR1I2 Antibody (6H11D8) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Western Blot

1:500-1:2000

Flow Cytometry Panel Builder

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PXR/NR1I2

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.;

Long Name

Pregnane X Receptor

Alternate Names

BXR, NR1I2, ONR1, PAR1, PAR2, SXR

Gene Symbol

NR1I2

Additional PXR/NR1I2 Products

Product Documents for PXR/NR1I2 Antibody (6H11D8) - BSA Free

Certificate of Analysis

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Product Specific Notices for PXR/NR1I2 Antibody (6H11D8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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