Highly potent NMDA antagonist; more active isomer. Shows some selectivity for NR2A-containing receptors (Ki
values are 0.041, 0.27, 0.63 and 1.99 μ
M for inhibition of NR2A-, NR2B-, NR2C- and NR2D-containing recombinant NMDA receptors respectively). (RS)-CPP
(Cat. No. 0173) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid.
Feng et al.
Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphono-2-enyl)piperazine-2-carboxylic acid (CPP-ene).
Aebischer et al.
The citations listed below are publications that use Tocris products. Selected citations for (R)-CPP include:
Showing Results 1 - 6 of 6