RASAL1 Antibody

Novus Biologicals | Catalog # NB100-55388

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all RASAL1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-QERGKAALGPLGP corresponding to C-Terminus according to NP_004649.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for RASAL1 Antibody

Western Blot: RASAL1 Antibody [NB100-55388]

Western Blot: RASAL1 Antibody [NB100-55388]

Western Blot: RASAL1 Antibody [NB100-55388] - (0.3ug/ml) staining of Human Thyroid lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for RASAL1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 90 kDa band observed in human thyroid gland lysates (calculated MW of 90.0 kDa band according to NP_004649.1). An additional band of unknown identity was also consistently observed at 21 kDa. This band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: RASAL1

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues.

Alternate Names

RAS protein activator like 1 (GAP1 like), RASALGAP1 like protein, rasGAP-activating-like protein 1

Entrez Gene IDs

8437 (Human)

Gene Symbol

RASAL1

UniProt

O95294 (Human)

Additional RASAL1 Products

Product Documents for RASAL1 Antibody

Certificate of Analysis

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Product Specific Notices for RASAL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for RASAL1 Antibody

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