Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Sheep IgG
View all Neurexin 1 beta/NXRN1b Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant rat Neurexin 1 beta isoform 1
Ala47-Thr392
Accession # Q63373

Specificity

Detects rat Neurexin 1 beta in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant rat Neurexin 1 alpha is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Rat Neurexin 1 beta /NXRN1b Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Rat Neurexin 1 beta /NXRN1b

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Neurexin 1 beta/NXRN1b

Neurexin 1 beta is an 80 kDa member of the Neurexin family of proteins. It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins. An alternate start site in the Neurexin 1 gene generate an alpha - (long) and beta - (short) isoform. Mature rat Neurexin 1 beta is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length. It has a 346 aa extracellular region (aa 47‑392) that contains one laminin-like G domain (aa 91‑264). Within the G domain, the presence or absence of a splice site (aa 201‑230) materially impacts neuroligin binding. Over aa 47‑392, rat Neurexin 1 beta is 100% and 98% aa identical to mouse and human Neurexin 1 beta, respectively.

Alternate Names

NXR1B, NXRN1b

Entrez Gene IDs

9378 (Human); 18189 (Mouse); 60391 (Rat)

Gene Symbol

NRXN1

UniProt

Q63373

Additional Neurexin 1 beta/NXRN1b Products

Product Documents for Rat Neurexin 1 beta /NXRN1b Biotinylated Antibody

Certificate of Analysis

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Product Specific Notices for Rat Neurexin 1 beta /NXRN1b Biotinylated Antibody

For research use only

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